Leapman affirms its commitment to the highest standards of research ethics, grounded in the principles of scholarly freedom, intellectual responsibility, and the imperative to minimize harm. Authors, editors, and reviewers must ensure that all research conducted under the scope of Leapman journals respects the dignity, rights, and safety of human and non-human subjects, upholds international ethical guidelines, and is presented with integrity, transparency, and sensitivity.
Scholarly Freedom and Scholarly Responsibility
Leapman upholds the fundamental right of researchers to pursue and communicate scientific inquiry free from censorship or institutional repression. This principle of academic freedom exists in tandem with an obligation to avoid foreseeable harm, maintain intellectual honesty, and ensure that scholarly communication does not contribute to the erosion of individual rights, public welfare, or ethical standards.
Benefits and Harms of Research
Research must be conducted with respect for all involved, including human participants, related individuals and communities, non-human life, ecosystems, and cultural heritage. Harm may arise directly through the research process—for example, injury to participants, suffering of animals, or environmental degradation—or indirectly through publication, such as stigmatization of marginalized groups or unintended policy consequences.
Research should maximize societal and intellectual benefit while minimizing risks. These principles of beneficence and non-maleficence are central to ethical frameworks including the Declaration of Helsinki, the Belmont Report, and international guidelines for health and social sciences. While the advancement of knowledge is a public good, the potential for harm may outweigh the value of certain research or its publication. Editors may therefore consult independent experts and may, in some cases, decline to publish, or subsequently retract, correct, or amend published material where the risk of harm is judged to be significant.
Research Involving Animals or Humans
All authors submitting manuscripts involving human or animal subjects must complete Leapman’s editorial policy checklist to confirm compliance with institutional, national, and international ethical standards.
Animal Research
Submissions reporting research involving live vertebrates or higher invertebrates must confirm that procedures were conducted in accordance with relevant regulatory frameworks. Authors must identify the approving institutional or licensing committee and provide any required reference numbers. Manuscripts must report animal characteristics relevant to the study outcomes and include housing and husbandry conditions where applicable. Leapman encourages adherence to the ARRIVE 2.0 guidelines and recommends consultation of the AVMA Guidelines for the Euthanasia of Animals (2020) for best practices.
Research with Human Participants, Their Data, or Biological Material
Studies involving human participants must comply with the Declaration of Helsinki. The approving ethics committee’s name and reference number must be provided. If the study was granted an ethics exemption, authors must identify the committee responsible for the exemption and state the grounds for approval. All manuscripts must include an explicit statement affirming that informed consent was obtained from all participants.
Research on Human Populations
Studies that involve populations classified by race, ethnicity, national or social origin, sex, gender identity, sexual orientation, religion, political opinion, age, disease status, disability, or socioeconomic status must clearly describe the basis for such categorization. Authors are required to define each group in terms of the study protocol, explain whether definitions were determined by participants, researchers, or funders, and justify the use of such groupings.
Authors must address how confounding variables were controlled and reflect on their own positionality when interpreting results involving groups to which they do not belong. The implications of classification choices must be considered carefully, and researchers must minimize the risk of misinterpretation or harm to studied populations. All manuscripts must use inclusive, respectful, and non-stigmatizing language. Stereotypes, cultural assumptions, or derogatory terminology are not acceptable. Unless directly relevant to the research question, demographic attributes should be omitted. Authors writing in English should consult the American Psychological Association’s guidelines on bias-free language.
Editors may require revisions, corrections, or in extreme cases, refuse publication or retract manuscripts if content:
– Assumes the superiority or inferiority of any group
– Undermines the dignity of individuals or groups
– Includes explicit or implicit disparagement
– Presents a singular privileged perspective as universally applicable
Race, Ethnicity, and Racism
Race and ethnicity are sociopolitical constructs, not biological classifications. Manuscripts must not use these categories as proxies for variables such as income or education. Researchers must disclose who determined classification terms (participants, researchers, or third parties) and how classification was performed.
Biomedical studies must distinguish genetic ancestry from race and ethnicity. Race/ethnicity may be relevant for studying health disparities but are not valid surrogates for biological mechanisms. When genetic ancestry data are unavailable and race/ethnicity are used, this must be justified with care and clarity. Racism is scientifically unfounded and ethically impermissible. Editors may decline, retract, or correct manuscripts with content that perpetuates racial or ethnic bias, using the same evaluative criteria outlined above.
Sex, Gender, and Sexual Orientation
Leapman supports the Sex and Gender Equity in Research (SAGER) guidelines and expects authors to apply these principles when relevant. Sex (biological traits) and gender (social roles and identity) must be clearly distinguished. Authors should state whether participants’ sex and gender were self-identified or assigned, and describe the methodology used.
Studies should report disaggregated data by sex and gender when collected, with consent for reporting individual-level data. Disaggregated results must be available in source data or study supplements. If sex- and gender-based analyses were pre-specified, results should be reported regardless of outcome. Post hoc analyses should be avoided if the study lacks statistical power. If such analyses were not performed, authors must explain why in the reporting summary.
Working definitions must be provided for:
– Sex: biological characteristics including chromosomes, anatomy, hormones
– Gender: socially constructed roles, behaviors, and identities
– Gender identity: internal sense of gender
– Gender presentation: external expression through behavior and appearance
Sexist, misogynistic, or anti-LGBTQ+ content is unacceptable. Editors may seek ethical review, request revisions, or decline manuscripts that perpetuate such content.
Studies Involving Vulnerable Groups
Studies involving vulnerable populations—where coercion is possible or consent may not be fully informed—will be subject to enhanced editorial oversight. The editor may refer manuscripts to a dedicated internal ethics committee. Authors must secure consent for any personally identifiable biomedical, clinical, or biometric data and provide supporting documentation if requested.
Publishing Images of Human Research Participants
When publishing identifiable images of research participants, authors must confirm that written informed consent for publication has been obtained. Anonymization methods such as black bars across the eyes are not acceptable. In certain cases, editors may request original consent documentation. Images without appropriate consent will be removed.
Clinical Trials
All interventional trials must be registered prior to enrollment. Registration must occur in a WHO-recognized database such as ClinicalTrials.gov or ISRCTN. Trial registration numbers must be listed in the abstract and methods section.
Reports of Phase II and III randomized controlled trials must comply with CONSORT guidelines. Failure to do so may delay review. Prognostic studies using tumor markers should follow REMARK recommendations.
Human Biospecimens
Descriptions of human biospecimens must follow the BRISQ guidelines, including Tier 1 data fields. This ensures sufficient transparency about sample collection, processing, and usage.
Human Transplantation Studies
Manuscripts must include a statement confirming that no organs or tissues were sourced from prisoners. Authors must describe the institutional channels through which materials were obtained. For retrospective studies, authors must state whether consent was obtained or waived by an ethics board.
Studies Involving Human Embryos, Gametes, and Stem Cells
Research involving human embryos, gametes, embryonic stem cells, or clinical applications of stem cells must comply with all applicable regulations. The manuscript must identify the ethics committees approving the work, confirm informed consent from donors or recipients, and describe donation terms. Editors may request copies of approvals and redacted consent forms.
Authors are encouraged to consult the ISSCR 2016 Guidelines. Editors may seek external expert advice, especially when manuscripts report modifications of the human germline. Leapman has established an internal monitoring group composed of senior editorial and policy leadership to evaluate such submissions.
Dual Use Research of Concern
Manuscripts containing information that could be misused to pose threats to public health, safety, agriculture, or national security will undergo dual-use risk assessment. If the risk outweighs the benefit, publication will be declined. Already published material may be corrected or withdrawn.
Authors must comply with all institutional and national dual-use regulations. If the manuscript contains potentially harmful material, authors must describe containment measures and disclose oversight approvals. All authors must complete the dual-use section of the Leapman reporting summary. Editors may refer such manuscripts to a dedicated editorial monitoring group with relevant biosecurity expertise.
Editorial Oversight and Ethics Declarations
Leapman supports active editorial responsibility in safeguarding ethical publication standards. Editors are authorized to seek external ethics guidance, request manuscript revisions, and in cases of substantive ethical conflict, decline or retract a manuscript. Leapman journals maintain historical documentation of policy decisions and provide transparency around ethical publishing debates through formal editorials and public statements.
Expanded Requirements for Dual Use Research of Concern
Authors must be aware of dual-use implications of their work and are expected to actively consider how their research findings, tools, data, or technologies might be intentionally misused outside the scientific context. Examples include threats to biosecurity, the environment, public safety, or national infrastructure. Where relevant, authors must disclose whether their work is subject to institutional or national dual-use oversight and provide documentation of approval where required. If a study involves potentially hazardous biological or chemical agents, authors must describe containment strategies and biosafety protocols in the manuscript.
Manuscripts that contain content of dual-use concern will be evaluated with heightened scrutiny. Editors may consult external reviewers with domain expertise in biosafety or national security. The risk of potential misuse may result in the manuscript being declined or in the imposition of additional pre-publication requirements. Editors reserve the right to request redactions, contextual disclaimers, or modifications that mitigate the risk of harm. Already published articles may be corrected, amended, or removed should unanticipated threats arise.
Leapman maintains an internal editorial oversight group tasked with reviewing submissions raising dual-use concerns. This group includes senior publishing executives and policy specialists who may recommend consultation with external bioethics or security advisors. The assessment process balances the public good of scientific advancement with the ethical imperative to prevent foreseeable misuse.
Editorial Commentary and Historical Oversight
Leapman recognizes that ethical standards evolve alongside scientific progress. In line with this, Leapman will regularly publish editorial statements clarifying the application of ethics policies in response to emerging research practices, societal developments, or evolving international frameworks. These declarations serve to uphold transparency and reinforce editorial accountability.
Published research that raises unanticipated ethical or societal concerns may be subject to post-publication review. Where necessary, Leapman editors may issue public editorial notices, expressions of concern, or formal retractions in accordance with COPE (Committee on Publication Ethics) guidelines.
Leapman draws on the historical precedents of major scholarly publishers who have published editorials concerning sensitive topics such as stem cell research, genetic manipulation, animal experimentation, and dual-use technologies. The editorial team is committed to reflecting on similar issues as they arise and will document Leapman’s ethical position through openly accessible editorial communications.
Leapman affirms that open science and editorial rigor are not mutually exclusive. The free exchange of ideas must be exercised with responsibility. As part of its ongoing commitment to ethical publishing, Leapman maintains a record of significant policy developments and actively engages in scholarly dialogue on the boundaries of responsible research dissemination.